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THE ANTIAGING BENEFITS OF SOY. Stephen Holt, MD, MRCP (UK), FRCPC, FACP, FACG, FACN, BioTherapies Inc., 9 Commerce Road, Fairfield NJ 07004 (Tel. 1-800-700-7325).

Fractions of soybeans with health giving properties are rapidly becoming the most popular category of dietary supplements. The mechanisms whereby soy may promote longevity have been overlooked despite considerable, contemporary research on soy-fractions. In an extensive review of the literature (Holt, S., Soya for Health, Mary Ann Liebert Publishers Inc., Larchmont NY), condition specific anti-aging benefits of soy have been characterized.

Hypothetical Mechanisms for the Role of Soy Diets in Promotion of Longevity.

Premature death due to:

Condition	Effects of Soya
Heart Disease	Promotes cardiovascular wellness
Hypertension and consequences	Lowers blood pressure
Cancer	Cancer preventative role, isoflavones
Renal Failure	Potential renal and prostate benefits

Morbidity in old age due to:

Condition	Effects of Soya
Heart disease	Promotes cardiovascular wellness, lowers cholesterol
Skeletal disorders	Certain soya foods prevent or treat osteoporosis.
Cancer	Cancer preventative and therapeutic (?) role
Failing Physiological functions	General good nutritional value

The soy dietary supplement GenistaÔ (a soy protein isolate with isoflavones) has been found to reduce cholesterol with a therapeutic equivalence to synthetic lowering drugs in Phase IV studies in more than 40 patients. Phyto-EstÔ has a composition of soy isoflavones that have been shown to treat osteoporosis, promote cardiovascular health and suppress menopausal symptoms. Soy products have no significant adverse effects in these formulations. Dietary supplements made from soy will accelerate the importance of condition specific nutritional management for the promotion of health and longevity.

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